منابع مشابه
Inflammed skin harbours Th9 cells.
Various effector CD4 + T-lymphocyte subsets have been characterized, such as T-helper (Th)1, Th2, regulatory CD4 + T cells (Treg), Th17, and Th22, which show distinct patterns of cytokine release. Specifically, the cytokine interleukin (IL)-9 has been regarded largely as an exclusive Th2 cytokine. However, a new subset of the Th population, named " Th9 " , which is separate from Th2, producing ...
متن کاملTh9 cells: differentiation and disease.
CD4(+) T-helper cells regulate immunity and inflammation through the acquisition of potential to secrete specific cytokines. The acquisition of cytokine-secreting potential, in a process termed T-helper cell differentiation, is a response to multiple environmental signals including the cytokine milieu. The most recently defined subset of T-helper cells are termed Th9 and are identified by the ...
متن کاملLangerhans Cells in Skin Lesions of Leprosy
Background: Langerhans cells are important in the pathogenesis of leprosy. A recent study reported that these cells were almost absent in the epidermis overlying lepromatous lesions. Objective: To investigate a possible relationship between the number of Langerhans cells and the histopathologic spectrum of lesions in patients with leprosy. Methods: An immunohistochemical staining for S100 prot...
متن کاملPrevalence of skin disorders in athletes of 10 sport activities
Participation in sport activities has become increasingly popular, as a result, more patients are referred 10 dermatologists for disorders caused by sport activities. During most forms of exercise, the skin and it's appendages are under constant assault by traumatic and other environmental factors that can cause injury. Physical activity also predispose s the skin to infection and can exacer...
متن کاملTh9 cells induce steroid-resistant bronchial hyperresponsiveness in mice.
BACKGROUND Reduced responsiveness to corticosteroid therapy is a major problem for patients with severe asthma. Although Th9 cells, along with Th2 cells, facilitate antigen-induced airway eosinophilia and bronchial hyperresponsiveness (BHR), the sensitivity of Th9 cell-mediated responses to steroid therapy remains unknown. In this study, we investigated the effect of dexamethasone (Dex) on anti...
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ژورنال
عنوان ژورنال: Seminars in Immunopathology
سال: 2016
ISSN: 1863-2297,1863-2300
DOI: 10.1007/s00281-016-0607-8